CNS Metastatic Disease
CNS Metastatic Disease
Circulating Brain Tumor Cells
BiographyDr. Brian Nahed is a neurosurgeon who specializes in brain tumors (glioblastoma, gliomas (low grade and high grade gliomas), metastatic brain tumors, and meningiomas) as well as Spinal Disorders.
Born in New York, Dr. Nahed attended UCLA where he majored in Neuroscience, graduating Phi Beta Kappa. He attended the Yale School of Medicine where he was awarded the Doris Duke Clinical Research Fellowship. Dr. Nahed completed his internship and neurosurgery residency at the Massachusetts General Hospital. Dr. Nahed completed a postdoctoral fellowship with Drs. Daniel Haber and Shyamala Maheswaran at the MGH Cancer Center.
Dr. Brian Nahed joined the MGH Department of Neurosurgery and Brain Tumor Center in 2011. He is an assistant professor and teaching faculty member of Harvard Medical School. Dr. Brian Nahed's research focuses on developing a blood based test to diagnose and monitor brain tumors. In collaboration with Drs. Haber, Maheswaran, and Stott, Dr. Nahed's recently published the first evidence of circulating tumor cells in the blood patients with glioblastoma. Dr. Nahed is actively enrolling patients into his translational clinical research study.
Dr. Brian Nahed's research focuses on identifying and analyzing circulating tumor cells in the blood of patients with brain cancer. Through a collaboration between bioengineers, molecular biologists and clinicians, a circulating tumor cell capture device was developed to capture and detect tumor cells from patients with cancer. Under the mentorship of Drs. Daniel Haber, Shyamala Maheswaran, and Mehmet Toner, they aim to harness this technology to genetically characterize tumor cells without needing an invasive biopsy, and determine responsiveness to targeted cancer drugs. It also offers the opportunity to study cancer stem cells or metastasic precursors, thought to be at the origin of cancer spread via the bloodstream, to define their molecular vulnerabilities and help design new therapies to prevent cancer metastasis.
Dr. Nahed's research was recently published in Cancer Discovery and he is active enrolling patients in his translational clinical research study. More information about his research lab can found at the the Nahed Brain Tumor Research Lab.
88 peer-reviewed publications to date. Please refer to the pubmed webste link for a complete list of the publications.
Dr. Brian Nahed's research project focuses on developing a blood based test to diagnose and monitor brain tumors. More information about his research lab can be found at the Nahed Brain Tumor Research Lab Website.
Brian V. Nahed, MD
Dr. Brian Nahed specializes in brain tumors and spinal disorders. As an attending neurosurgeon at the Massachusetts General Hospital, he has appointments with the MGH Cancer Center, Stephen E. and Catherine Pappas Center for Neurooncology and is a faculty member of the Harvard Medical School. Dr. Nahed's research focuses on circulating tumor cells and metastatic disease. In collaboration with Drs. Shannon Stott, Daniel Haber and Shyamala Maheswaran, Dr. Nahed's research has received several grants supporting his laboratory effort at the MGH Cancer Center.
Collaborators & Co-Authors
Brian V. Nahed MD & Co-authors; - Profiles found at Harvard Catalyst:
Some Recent Publications via PubMed - Search Terms CNS Metastatic Disease AND MGH